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US 8,604,172 B2Granted
Humanized antibody compositions and methods for binding lysophosphatidic acid
AssigneeLpath, Inc.
InventorsRoger A. Sabbadini, William A. Garland, Genevieve Hansen, Steven Tarran Jones, David Gareth Williams
Life of this patent
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Abstract
Compositions and methods for making and using humanized anti-LPA monoclonal antibodies, and fragments and derivatives thereof, are described.
Claims5
An antibody or antigen-binding antibody fragment that binds lysophosphatidic acid (LPA) under physiological conditions, wherein each immunoglobulin heavy chain variable domain comprises the amino acid sequence of SEQ ID NO:
- 189 and each immunoglobulin light chain variable domain comprises the amino acid sequence of SEQ ID NO:
- 169.
Dependencies are inferred from the claim text.