Systems, methods and compositions for optical stimulation of target cells
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsKarl Deisseroth, Feng Zhang, Viviana Gradinaru
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Abstract
Methods, systems and devices are implemented in connection with light-responsive ion channel molecules. One such method is implemented using a light-activated ion channel molecule that responds to a light stimulus. The method includes engineering the light-activated ion channel molecule in a cell; and activating the ion channel molecule, in response to light stimulus that is provided to the ion channel molecule and that has properties that do not activate a ChR2 ion channel, to allow ions to pass through the light-activated ion channel molecule.
Claims14
A method for modulating the activity of a cell engineered to express a Volvox carteri light-responsive ion channel protein (VChR1), the method comprising:
- activating the light-responsive VChR1 protein with light.
Dependencies are inferred from the claim text.