Sealing members, articles using the same and methods of reducing sticktion
AssigneeBecton, Dickinson and Company
InventorsYongming Liu, Xia Zhao
Life of this patent
Estimating the term…
Abstract
The present invention provides rubber sealing members having an exterior surface adapted to sealingly engage an inner surface of a chamber of the medical device, the exterior surface of the sealing member having a coating thereon prepared from a curable composition including: (a) a first organopolysiloxane having at least two alkenyl groups; and (b) a second organopolysiloxane having at least two pendant hydrogen groups, the second organopolysiloxane being different from the first organopolysiloxane, wherein at least one of the first organopolysiloxane, the second organopolysiloxane or an optional third organopolysiloxane of the curable composition comprises a fluoro group.
Claims56
A syringe assembly comprising:
- (a) a chamber comprising an inner surface for containing a medicament;
- and
- (b) a rubber sealing member formed from silicone rubber and having an exterior surface adapted to sealingly engage an inner surface of a chamber of the syringe assembly, the exterior surface of the sealing member having a coating thereon prepared from a curable composition comprising:
- (a) a first organopolysiloxane comprising at least two alkenyl groups;
- (b) a second organopolysiloxane comprising at least two pendant hydrogen groups, the second organopolysiloxane being different from the first organopolysiloxane;
- and
- (c) a cyclic organosiloxane.
A method for lubricating the interface between an inner surface of a chamber and an exterior surface of a silicone rubber sealing member of a syringe assembly, comprising the steps of:
- (a) applying a coating onto the exterior surface of the silicone rubber sealing member, the coating being prepared from a curable composition comprising:
- (i) a first organopolysiloxane comprising at least two alkenyl groups;
- (ii) a second organopolysiloxane comprising at least two pendant hydrogen groups, the second organopolysiloxane being different from the first organopolysiloxane;
- and
- (iii) a cyclic organosiloxane;
- and
- (b) at least partially crosslinking the coating of step (a).
A method for reducing breakout force or breakloose force between an inner surface of a chamber and an exterior surface of a silicone rubber sealing member of a syringe assembly, comprising the steps of:
- (a) applying a coating onto the exterior surface of the silicone rubber sealing member, the coating being prepared from a curable composition comprising:
- (i) a first organopolysiloxane comprising at least two alkenyl groups;
- (ii) a second organopolysiloxane comprising at least two pendant hydrogen groups, the second organopolysiloxane being different from the first organopolysiloxane;
- and
- (iii) a cyclic organosiloxane;
- and
- (b) at least partially crosslinking the coating of step (a).
A method for reducing sustaining force between an inner surface of a chamber and an exterior surface of a silicone rubber sealing member of a syringe assembly, comprising the steps of:
- (a) applying a coating onto the exterior surface of the silicone rubber sealing member, the coating being prepared from a curable composition comprising:
- (i) a first organopolysiloxane comprising at least two alkenyl groups;
- (ii) a second organopolysiloxane comprising at least two pendant hydrogen groups, the second organopolysiloxane being different from the first organopolysiloxane;
- and
- (iii) a cyclic organosiloxane;
- and
- (b) at least partially crosslinking the coating of step (a).
A method for reducing breakloose and sustaining forces between an inner surface of a chamber and an exterior surface of a silicone rubber sealing member of a syringe assembly, comprising the steps of:
- (a) applying a coating onto the exterior surface of the silicone rubber sealing member, the coating being prepared from a curable composition comprising:
- (i) a first organopolysiloxane comprising at least two alkenyl groups;
- (ii) a second organopolysiloxane comprising at least two pendant hydrogen groups, the second organopolysiloxane being different from the first organopolysiloxane;
- and
- (iii) a cyclic organosiloxane;
- and
- (b) at least partially crosslinking the coating of step (a).
A syringe assembly comprising:
- (a) a chamber comprising an inner surface for containing a medicament;
- and
- (b) a rubber sealing member formed from silicone rubber and having an exterior surface adapted to sealingly engage an inner surface of a chamber of the syringe assembly, the exterior surface of the sealing member having a coating thereon prepared from a curable composition comprising:
- (a) a first organopolysiloxane comprising at least two alkenyl groups;
- and
- (b) a second organopolysiloxane comprising at least two pendant hydrogen groups, the second organopolysiloxane being different from the first organopolysiloxane,
- wherein at least one of the first organopolysiloxane and the second organopolysiloxane of the curable composition comprises at least one fluoro group.
A method for lubricating the interface between an inner surface of a chamber and an exterior surface of a silicone rubber sealing member of a syringe assembly, comprising the steps of:
- (a) applying a coating onto the exterior surface of the rubber sealing member, the coating being prepared from a curable composition comprising:
- (i) a first organopolysiloxane comprising at least two alkenyl groups;
- and
- (ii) a second organopolysiloxane comprising at least two pendant hydrogen groups, the second organopolysiloxane being different from the first organopolysiloxane,
- wherein at least one of the first organopolysiloxane and the second organopolysiloxane comprises at least one fluoro group;
- and
- (b) at least partially crosslinking the coating of step (a).
A method for reducing breakout force or breakloose force between an inner surface of a chamber and an exterior surface of a silicone rubber sealing member of a syringe assembly, comprising the steps of:
- (a) applying a coating onto the exterior surface of the rubber sealing member, the coating being prepared from a curable composition comprising:
- (i) a first organopolysiloxane comprising at least two alkenyl groups;
- and
- (ii) a second organopolysiloxane comprising at least two pendant hydrogen groups, the second organopolysiloxane being different from the first organopolysiloxane,
- wherein at least one of the first organopolysiloxane and the second organopolysiloxane comprises at least one fluoro group;
- and
- (b) at least partially crosslinking the coating of step (a).
A method for reducing sustaining force between an inner surface of a chamber and an exterior surface of a silicone rubber sealing member of a syringe assembly, comprising the steps of:
- (a) applying a coating onto the exterior surface of the rubber sealing member, the coating being prepared from a curable composition comprising:
- (i) a first organopolysiloxane comprising at least two alkenyl groups;
- and
- (ii) a second organopolysiloxane comprising at least two pendant hydrogen groups, the second organopolysiloxane being different from the first organopolysiloxane,
- wherein at least one of the first organopolysiloxane and the second organopolysiloxane comprises at least one fluoro group;
- and
- (b) at least partially crosslinking the coating of step (a).
A method for reducing breakloose and sustaining forces between an inner surface of a chamber and an exterior surface of a rubber sealing member of a syringe assembly, comprising the steps of:
- (a) applying a coating onto the exterior surface of the rubber sealing member, the coating being prepared from a curable composition comprising:
- (i) a first organopolysiloxane comprising at least two alkenyl groups;
- and
- (ii) a second organopolysiloxane comprising at least two pendant hydrogen groups, the second organopolysiloxane being different from the first organopolysiloxane,
- wherein at least one of the first organopolysiloxane and the second organopolysiloxane comprises at least one fluoro group;
- and
- (b) at least partially crosslinking the coating of step (a).
Dependencies are inferred from the claim text.