Pharmaceutical compositions resistant to abuse

An abuse-resistant pharmaceutical composition comprising a shell resistant to physical tampering, the shell comprising an outer shell wall having an inner surface and an outer surface, the outer surface being a double curved surface,

• wherein the shell extends from a first end to a second end, the shell having a length in the range of from 4 mm to 20 mm,
• wherein the outer shell wall has a first opening at the first end and a second opening at the second end, the first opening and the second opening having an area in the range of from about 1 mm2 to about 100 mm2, and
• wherein the outer shell wall is of varying thickness and has a maximum thickness in a range of from 1 mm to about 10 mm, the outer shell wall being impermeable to water.