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US 8,603,495 B2Granted
Compositions and methods for biological remodeling with frozen particle compositions
AssigneeThe Invention Science Fund I, LLC
InventorsEdward S. Boyden, Daniel B. Cook, Roderick A. Hyde, Eric C. Leuthardt, Nathan P. Myhrvold, Elizabeth A. Sweeney, Lowell L. Wood, Jr.
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Abstract
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
Claims12
A frozen particle composition, comprising:
- one or more frozen particles coated with at least one neuro-muscular toxin and further include at least one biological remodeling agent including collagen and one or more of vitamin A, vitamin C, fibrin, thrombin, hyaluronic acid, hydroxylapatite, keratin, fibrinogen, hyaluronate, chitin, chitosan, methylcellulose, alginate, cellulose, polyaldehyde glucornate, Factor XIII, Factor XII, silicone, polyurethane, elastin, glycosaminoglycan, poly(alpha-hydroxyacid), or glutaraldehyde;
- wherein the one or more frozen particles have at least one major dimension of approximately one micrometer or less, approximately one nanometer or less, or any value therebetween.
Dependencies are inferred from the claim text.