Biochip for archiving and laboratory-medical analysis of biological sample material, process for its production, and its use in diagnostic methods

A diagnostic detection method for detecting the presence or absence of analytes in a biological sample material, comprising the steps of:

• a) making a biochip by binding said biological sample material which is obtained from body fluids or cells or tissue samples from an organism to be examined to a surface of a sample carrier, which surface is subdivided into micro-areas, by coating with a liquid or suspended sample material of said biological sample material, and subsequently drying, whereby said analytes which are present in the biological sample material are bound to said surface in a manner that does not specifically select a molecule;
• b) selecting at least one specific, diagnostic detection reagent that is known to specifically interact with or bind to said analyte;
• c) applying said at least one specific, diagnostic detection reagent to single micro-areas of the biochip, using a pipetting robot, and incubating under conditions suitable for the relevant detection reaction by which said reagent interacts with or binds to said analyte;
• d) applying wash liquids to suppress unspecific reactions, and subsequently drawing-off of these wash liquids;
• e) detecting measurement signals from positively reacting micro-areas;
• evaluating the signals for the presence or absence of the analytes and storing the measurement data.