# US 8,585,286 B2 · Spectral detector calibration

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- Number: US 8,585,286 B2
- Document ID: US8585286B2
- Status: Granted
- Kind: B2
- Application number: 12/934,661
- Filed: 2009-03-20
- Published: 2011-01-20
- Granted: 2013-11-19
- Earliest claimed: 2008-04-01
- Assignees: Koninklijke Philips N.V.
- Applicants: Amir Livne; Naor Wainer; Jens-Peter Schlomka; Ewald Roessl; Roland Proksa
- Inventors: Amir Livne; Naor Wainer; Jens-Peter Schlomka; Ewald Roessl; Roland Proksa
- Web page: https://patentgrep.com/patent/US8585286B2

## CPC

- G01T 7/005: {calibration techniques (stabilization of spectrometer G01T1/40)}
- A61B 6/032: {Transmission computed tomography [CT]}
- A61B 6/4042: {K-edge filters}
- A61B 6/482: {involving multiple energy imaging}
- A61B 6/585: {Calibration of detector units}
- G01T 1/1647: {Processing of scintigraphic data (not related to a particular imaging system G01T1/2992)}
- A61B 6/4035: {the source being combined with a filter or grating}
- A61B 6/4441: {the rigid structure being a C-arm or U-arm}
- G01N 2223/3037: standards (constitution)
- G01T: MEASUREMENT OF NUCLEAR OR X-RADIATION (radiation analysis of materials, mass spectrometry G01N23/00; tubes for determining the presence, intensity, density or energy of radiation or particles H01J47/00)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)

## Abstract

A method includes detecting radiation that traverses a material having a known spectral characteristic with a radiation sensitive detector pixel that outputs a signal indicative of the detected radiation and determining a mapping between the output signal and the spectral characteristic. The method further includes determining an energy of a photon detected by the radiation sensitive detector pixel based on a corresponding output of the radiation sensitive detector pixel and the mapping.

## Claims

### Claim 1

A method, comprising:
detecting generated radiation that traverses a material having a known spectral attenuation or fluorescence characteristic with a radiation sensitive detector pixel that outputs a signal indicative of the detected radiation,
wherein the radiation is generated by an imaging system, the material is located in a filter tray of the imaging system, and the filter tray is movable to selectively move the material into and out of the generated radiation;
counting a number of times a peak amplitude of the output signal exceeds each of a plurality of different thresholds corresponding to an output range of the detector pixel; and
determining a mapping between the output signal of the pixel and the known spectral characteristic, wherein the mapping is based on a distribution of the counts over the output range.

### Claim 2 (depends on 1)

The method of claim 1, further including determining an energy of a photon detected by the radiation sensitive detector pixel based on a corresponding output of the radiation sensitive detector pixel and the mapping.

### Claim 3 (depends on 1)

The method of claim 1, further including locating the spectral characteristic in the distribution based on an accumulation of the counts over the output range.

### Claim 4 (depends on 1)

The method of claim 1, further including differentiating the distribution one or more times to identify a peak in the differentiated distribution that corresponds to the spectral characteristic.

### Claim 5 (depends on 1)

The method of claim 1, further including:
comparing a peak amplitude of the output signal with a plurality of different thresholds that represent an output range of the detector pixel;
counting a number of times the peak amplitude exceeds each of the thresholds; and
mapping the output signal of the pixel and the known spectral characteristic based on a distribution of an accumulation of the counts over the output range.

### Claim 6 (depends on 1)

The method of claim 1, wherein the signal is indicative of an energy of a detected photon.

### Claim 7 (depends on 1)

The method of claim 1, wherein the spectral characteristic is a k-absorption edge of the material.

### Claim 8 (depends on 1)

The method of claim 1, wherein the material includes one of silver, tin, gadolinium, antimony, iodine, barium, lutetium, gold, lead, bismuth, or uranium.

### Claim 9

An imaging system, comprising:
a radiation source that emits radiation that traverses an examination region;
a tray located near the radiation source, wherein the tray includes a material with known spectral characteristics, and the tray is movable to selectively position the material in a path of the emitted radiation;
a spectral detector that detects radiation that traverses the material and the examination region;
a calibration component that calibrates the spectral detector based on the detected radiation;
a count accumulator that accumulates counts representing a number of times a peak value of the output signal exceeds each of a plurality of different threshold values; and
a mapper that maps a peak value of the accumulated counts to a k-edge energy of the material, wherein the calibration component generates a calibration for the spectral detector based on the mapping.

### Claim 10 (depends on 9)

The imaging system of claim 9, wherein the material has a known k-edge, and the detector outputs a signal indicative of the energy of detected radiation, and wherein the calibration component generates a calibration based on the k-edge of the material and the output value of the spectral detector.

### Claim 11 (depends on 9)

The imaging system of claim 9, wherein the calibration component further includes:
a peak enhancer that enhances the peak value of the accumulated counts prior to the mapping.

### Claim 12 (depends on 11)

The imaging system of claim 11, wherein the peak enhancer differentiates the accumulated counts to enhance the peak value of the accumulated counts.

### Claim 13 (depends on 9)

The imaging system of claim 9, further including:
an energy discriminator that energy discriminates the output signal based the thresholds; and
a counter that counts a number of times the peak value of the output signal exceeds a threshold, for each of the thresholds.

### Claim 14

A method for calibrating a detector array of an imaging system, comprising:
detecting fluorescence radiation having a known spectral characteristic with a radiation sensitive detector pixel of the detector array, which outputs a signal indicative of an energy of the detected fluorescence radiation;
determining a mapping between the output signal and the known spectral characteristic; wherein the mapping is based on a distribution of counts over an output range of a detector pixel detecting the radiation; and
determining a calibration for the detector array of the imaging system based on the mapping.

### Claim 15 (depends on 14)

The method of claim 14, further including:
generating the fluorescence radiation by irradiating a material having the known spectral characteristic with x-radiation, wherein the material emits the fluorescence radiation.

### Claim 16 (depends on 15)

The method of claim 15, further including:
employing the calibration to set at least one energy threshold of a photon energy-discriminator of the system.

### Claim 17 (depends on 14)

The method of claim 14, further including:
determining a feature of the output signal, wherein the feature is indicative of the energy of the detected fluorescence radiation; and
mapping the feature to the known spectral characteristic.

### Claim 18 (depends on 17)

The method of claim 17, wherein the feature includes at least one of a peak amplitude of an emission distribution of the detected fluorescence radiation, an amplitude increase in the distribution greater than a first threshold, or an amplitude decrease in the distribution greater than a second threshold.

### Claim 19 (depends on 14)

The method of claim 14, further including generating the fluorescence radiation by alternatively illuminating at least one high energy emitter with radiation produced by an x-ray tube of the imaging system and at least one low energy emitter with radiation produced by an x-ray tube of the imaging system.

### Claim 20 (depends on 19)

The method of claim 19, further including:
generating a calibration curve based on a first mapping using a first output signal of the detector array corresponding to the at least one low energy emitter and on a second mapping using a second output signal of the detector array corresponding to the at least one high energy emitter.

### Claim 21

An imaging system, comprising:
a radiation source that emits first radiation that traverses an examination region;
a detector array that detects the first radiation and generates a signal indicative thereof;
a detector calibration apparatus; including:
a radiation block that blocks the first radiation from illuminating the detector array; and
at least one target that receives the first radiation and generates second radiation that includes a known spectral characteristic and that illuminates the detector array; and
a calibration component that generates a calibration for the detector array based on an identified known spectral characteristic of the second radiation and a pre-determined spectral characteristic of the target.

### Claim 22 (depends on 21)

The system of claim 21, further including:
a feature identifier that identifies the known spectral characteristic in the second radiation.

### Claim 23 (depends on 21)

The system of claim 21, wherein the calibration correlates the identified spectral characteristic and the pre-determined spectral characteristic.

### Claim 24 (depends on 21)

The system of claim 21, wherein the identified spectral characteristic includes at least one of a peak amplitude of an emission distribution corresponding to the second radiation, an amplitude increase in the distribution greater than a first threshold, or an amplitude decrease in the distribution greater than a second threshold.

### Claim 25 (depends on 21)

The system of claim 21, wherein the radiation block is selectively moveable between a first position at which it blocks the transmission radiation and at least a second position at which it does not block the transmission radiation.

### Claim 26 (depends on 21)

The system of claim 21, wherein the target includes at least two materials, each having a different spectral characteristic.

### Claim 27 (depends on 26)

The system of claim 26, wherein the at least two materials are alternately positioned in a path of the first radiation, and a first spectral characteristic is identified for one of the at least two materials and a second spectral characteristic is identified for another of the at least two materials, and the calibration component generates the calibration based on the first and second spectral characteristics.

### Claim 28

A system, comprising:
a detector calibration apparatus; including:
a radiation block that blocks first radiation from illuminating a detector array, wherein the first radiation is emitted by a radiation source and traverses an examination region and the detector array detects the first radiation and generates a signal indicative thereof; and
at least one target that receives the first radiation and generates second radiation that includes a known spectral characteristic and that illuminates the detector array; and
a calibration component that generates a calibration for the detector array based on an identified known spectral characteristic of the second radiation and a pre-determined spectral characteristic of the target.

### Claim 29 (depends on 28)

The apparatus of claim 28, wherein the radiation block and/or the target is removably mounted to the system when calibrating the detector array and removed from the system when scanning an object or subject.

### Claim 30 (depends on 28)

The apparatus of claim 28, wherein the target includes at least two materials that emit radiation having a different known spectral characteristics.
