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US 8,577,470 B2Granted
Systems and methods for improving memory in Alzheimer's patients
OwnerSouhile Assaf, Mandar Joginventors
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Abstract
In many aspects, the invention relates to systems and methods for providing memory therapy by modulating neural firing rhythms, in particular in Alzheimer's patients. The stimulation of neurons is controlled through a feedback process whereby neuron firing rhythms are altered based on naturally occurring electrical and chemical activity in the brain. Neurons in the nucleus basalis and dentate gyrus may be targeted in order to establish neural signaling pathways and establish communication between these regions.
Claims18
A method of improving memory function in a patient, comprising:
- (a) receiving a set of inputs from the dentate gyrus (DG) in a patient's brain,
- (b) correlating the set of inputs with a set of neurophysiological markers of memory function, and
- (c) improving the memory function in the patient's brain by inducing a response in the nucleus basalis (NB) of the brain, which response is selected based upon the correlations of step (b).
Dependencies are inferred from the claim text.