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US 8,577,456 B2Granted
Measuring autonomic tone using atrioventricular delay
AssigneeCardiac Pacemakers, Inc.
InventorsBarun Maskara, Robert Shipley, Stephen Ruble
Life of this patent
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Abstract
An autonomic status indicator representative of a sympathetic/parasympathetic balance of a subject can use atrioventricular (AV) delays measured during recovery from (or in response to) elevated atrial pacing while the subject is at rest.
Claims20
A system comprising:
- a cardiac rhythm management device, the cardiac rhythm management device comprising:
- an atrial pacing circuit, configured to provide, during a testing time period, atrial pacing to a subject at rest, over a specified range of atrial pacing rates or intervals;
- and
- an intrinsic AV delay measurement circuit, configured to:
- measure, during the testing time period, intrinsic AV delays of the subject, over the specified range of atrial pacing rates or intervals;
- determine a baseline intrinsic AV delay of the subject at rest during a time other than the testing time period;
- and
- in response to and after the atrial pacing is terminated, measure intrinsic AV delays of the subject during a recovery time period;
- determine a duration of the recovery time period based on the measured intrinsic AV delays;
- and
- a processor, included in or coupled to the cardiac rhythm management device, the processor configured to use information about the duration of the recovery time period of the intrinsic AV delay to determine a first autonomic status indicator representative of a sympathetic/parasympathetic balance of the subject.
8 more elements
A method comprising:
- during a testing time period, using a cardiac rhythm management device for providing atrial pacing to a subject at rest, over a specified range of atrial pacing rates or intervals;
- during the testing time period, using the cardiac rhythm management device for measuring intrinsic AV delays of the subject, over the specified range of atrial pacing rates or intervals;
- determining a baseline intrinsic AV delay of the subject at rest during a time other than the testing time period;
- in response to and after the atrial pacing is terminated, using the cardiac rhythm management device for measuring intrinsic AV delays of the subject during a recovery time period;
- determining a duration of the recovery time period based on the measured intrinsic AV delays;
- using information about the duration of the recovery time period of the intrinsic AV delay to determine, using a processor, a first autonomic status indicator representative of a sympathetic/parasympathetic balance of the subject;
- and
- providing information about the first autonomic status indicator to the user or automated process.
5 more elements
Dependencies are inferred from the claim text.