Assay image acquisition system and method
AssigneeMolecular Devices, LLC
InventorSamuel Ascher Marquiss
Life of this patent
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Abstract
A computer-implemented method of imaging an assay sample having a set of individual samples using a camera is provided. A set of image frames is received. The set of image frames corresponds to an image stream of the assay obtained by the camera. A set of measurement results is identified. Individual measurement results in the set of measurement results are respectively associated with individual image frames in the set of image frames. A subset of measurement results is selected based, at least in part, on an exposure time. Individual measurement results in the subset of measurement results are combined to obtain an integrated measurement result.
Claims18
A computer-implemented method of imaging an assay sample having a set of individual samples using a camera, the computer-implemented method comprising:
- receiving a set of image frames by an image processing module, the set of image frames corresponds to an image stream of the assay sample obtained by the camera with a frame grabber;
- identifying a set of measurement results where individual measurement results in the set of measurement results are respectively associated with individual image frames in the set of image frames;
- selecting, based at least in part on an exposure time, a subset of measurement results from the set of measurement results;
- and
- combining individual measurement results in the subset of measurement results to obtain an integrated measurement result;
- wherein individual image frames in the set of image frames include an array of subsections, the subsections respectively correspond to individual samples in the assay sample;
- the set of measurement results is a data table of numerical values;
- and
- individual values in the data table respectively correspond measurement results for individual subsections in the array of subsections.
A system for imaging an assay sample having a set of individual samples using a camera, the system comprising:
- an image processing module that receives a set of image frames, the set of image frames corresponds to an image stream of the assay sample obtained by the camera and individual image frames in the set of image frames include an array of subsections respectively correspond to individual samples in the assay sample and respectively correspond to individual measurement results in a set of measurement results, which are presented as a data table of numerical values;
- where individual values in the data table respectively correspond measurement results for individual subsections in the array of subsections;
- and
- where the imaging processing module selects, based at least in part on an exposure time, a subset of measurement results from the set of measurement results and combines individual measurement results in the subset of measurement results to obtain an integrated measurement result.
A computer-implemented method of imaging an assay sample having a set of individual samples using a camera, the computer-implemented method comprising:
- obtaining an image stream of the assay sample with an image processing module of the camera during an imaging period;
- sampling the image stream during the imaging period to obtain a set of image frames, the image frames correspond to the image stream;
- performing one or more image correction operations on individual image frames in the set of image frames by an image correction module to obtain a set of corrected image frames;
- converting the set of corrected image frames by an image conversion module to obtain a set of measurement results;
- selecting a subset of measurement results from the set of measurement results based, at least in part, on an exposure time;
- and
- combining individual measurement results in the subset of measurement results by an image integration module to obtain an integrated measurement result;
- wherein individual image frames in the set of image frames include an array of subsections, the subsections respectively correspond to individual samples in the assay sample;
- the set of measurement results is a data table of numerical values;
- and
- individual values in the data table respectively correspond measurement results for individual subsections in the array of subsections.
Dependencies are inferred from the claim text.