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US 8,575,373 B2Granted
Crystalline forms of cabazitaxel
AssigneeScinoPharm Taiwan, Ltd.
InventorsJulian Paul Henschke, TsungYu Hsiao, MengFen Ho, YuanChang Huang
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Abstract
The present invention provides crystalline forms, including an anhydrate form, of cabazitaxel and processes for the preparation of these forms, designated as Forms C1, C2, C3, C4, C5, C6, C7, C8, C8b, C9 and C9p.
Claims18
A crystalline form of cabazitaxel selected from the dimethyl sulfoxide solvate or the acetic acid solvate, wherein said crystalline form is substantially free of other crystalline forms;
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- the dimethyl sulfoxide solvate is characterized by an XRPD pattern that comprises peaks at 7.97, 8.8, and 9.4 (±0.1 degrees 2θ);
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- the acetic acid solvate is characterized by an XRPD pattern that comprises peaks at 7.2, 8.2, 8.7, and 9.3 (±0.1 degrees 2θ).
1 more element
Dependencies are inferred from the claim text.