Back to results
US 8,575,361 B2Granted
Tetrahydronaphthalene derivatives
AssigneeConcert Pharmaceuticals, Inc.
InventorsRoger Tung, Craig E. Masse
Life of this patent
Estimating the term…
Abstract
This invention relates to novel tetrahydronaphthalene derivatives, and pharmaceutically acceptable salts thereof according to the following formulae, in one embodiment: as described herein. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering a selective T-type calcium channel blocker.
Claims3
A compound of Formula C:
- which is Compound 703a, or a pharmaceutically acceptable salt thereof, wherein in Compound 703a:
- R1 is CD3;
- Y8 and Y9 are each hydrogen;
- Ra and Rb are each —CH3;
- each of Y3a, Y3b, Y5a, and Y5b is hydrogen;
- each of Y2a, Y2b, Y6a, Y6b, Y7aand Y7b is D;
- is CH2OCH3, and
- wherein any atom not designated as deuterium is present at its natural isotopic abundance.
5 more elements
Dependencies are inferred from the claim text.