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US 8,575,351 B2Granted
Active metabolite of a thrombin receptor antagonist
AssigneeMerck Sharp & Dohme Corp.
InventorsKimberly Nguyen Voronin, Natalia A. Penner
Life of this patent
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Abstract
Disclosed herein is an active metabolite (“M20”) of a molecule that is useful as a thrombin receptor antagonist: Also disclosed are formulations of this compound, synthetic routes to this compound, and methods of treating a variety of cardiovascular conditions, including acute coronary syndrome and peripheral arterial disease, and of effecting secondary prevention, by orally administering the active metabolilte.
Claims7
A compound of the following formula:
- or a pharmaceutically acceptable salt or hydrate thereof in an isolated or purified form.
A pharmaceutical composition comprising an effective amount of a compound of the formula
- or a pharmaceutically acceptable salt or hydrate thereof, and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.