Population scale HLA-typing and uses thereof
AssigneeGenomics USA, Inc.
InventorsKrishna Jayaraman, Rahul Mitra, Michael E Hogan, Frederick H Eggers
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Abstract
The present invention provides a portable system for real-time population-scale HLA genotyping and/or allelotyping in a field environment and methods of such population-scale HLA genotyping. The individual components of the system are portable to and operable within a field environment thereby providing high throughput with real-time geno- or allelotyping. Also provided are HLA gene-specific primers and HLA allele-specific or single nucleotide polymorphism-specific hybridization probes. In addition the present invention provides a microarray comprising the hybridization probes. Further provided is a kit comprising the HLA gene-specific primers and the microarray.
Claims6
Hybridization probes for detecting single nucleotide polymorphisms (SNPs) in an HLA gene, wherein said hybridization probes are selected from the group consisting of SEQ ID Numbers 159, 162, 240, and 242.
Dependencies are inferred from the claim text.