Pharmaceutical compositions of aripiprazole
AssigneeZysis Limited
InventorsIan Wilding, Russell Pendleton
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Abstract
An orally deliverable pharmaceutical composition provides controlled release of aripiprazole. The composition includes a therapeutically effective amount of aripiprazole and at least one pharmaceutically acceptable excipient. The compositions of the invention may exhibit one or more of the release profiles defined in the specification.
Claims13
A method of treating a patient with one or more of a neurological and a psychiatric condition selected from the group consisting of schizophrenia, bipolar disorder, schizoaffective disorders, and combinations thereof, the method comprising orally administering to the patient once weekly a pharmaceutical composition for the controlled release of aripiprazole, the pharmaceutical composition comprising a therapeutically effective amount of aripiprazole and at least one release-retarding material comprising a water-swellable polymer that forms a matrix that retards the release of the aripiprazole such that the aripiprazole released from the composition is effective in treating the neurological or psychiatric condition for a period of one week.
Dependencies are inferred from the claim text.