Pharmaceutical uses of staurosporine derivatives
AssigneeNovartis AG
InventorSteven Coutre
Life of this patent
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Abstract
This application relates to the use of staurosporines derivatives for the curative, palliative or prophylactic treatment of allergic rhinitis, allergic dermatitis, drug allergy or food allergy, angioedema, urticaria, sudden infant death syndrome, bronchopulmonary aspergillosis, multiple sclerosis, or mastocytosis; and to a method of treatment of warm-blooded animals in which a therapeutically effective dose of a compound of a Staurosporine Derivative is administered to a warm-blooded animal suffering from one of the diseases or conditions mentioned above.
Claims19
A method of treating mastocytosis, which comprises administering a therapeutically effective amount of a compound of formula (VII)
- or a pharmaceutically acceptable salt thereof,
- to a human patient suffering from mastocytosis, wherein the human patient ha KIT tyrosine kinase receptor with a D816V mutation.
A method of treating mastocytosis with resistance to imatinib, which comprises administering a therapeutically effective amount of a compound of formula (VII)
- or a pharmaceutically acceptable salt thereof,
- to a patient suffering from mastocytosis with resistance to imatinib and wherein the patient ha KIT tyrosine kinase receptor with a D816V mutation.
Dependencies are inferred from the claim text.