Aminocarboxylic acid derivative and medicinal use thereof
AssigneeOno Pharmaceutical Co., Ltd.
InventorsHiromu Habashita, Haruto Kurata, Shinji Nakade
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Abstract
The present invention relates to a compound represented by the formula (I), a salt thereof, an N-oxide form thereof, a solvate thereof, or a prodrug thereof, and a medicament containing the same. The compound represented by the formula (I) has an ability to bind to an S1P receptor (particularly, EDG-1, EDG-6, and/or EDG-8) and is useful for preventing and/or treating for rejection to transplantation, graft-versus-host disease, autoimmune diseases, allergic diseases, neurodegenerating diseases, and the like. wherein all symbols are described in the specification.
Claims4
1-[(6-{[2,4-bis(trifluoromethyl)benzyl]oxy}-1-methyl-3,4-dihydro-2-naphthalenyl)methyl]-3-azetidinecarboxylic acid, a salt thereof, an N-oxide form thereof, a solvate thereof or a prodrug thereof.
A compound which is 1-[(6-{[2,4-bis(trifluoromethyl)benzyl] oxy}-1-methyl-3,4-dihydro-2-naphthalenyl)methyl]-3-azetidinecarboxylic acid.
Dependencies are inferred from the claim text.