Amides of hyaluronic acid and the derivatives thereof and a process for their preparation
AssigneeFidia Farmaceutici S.P.A.
InventorsDavide Bellini, Alessandra Topai
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AssigneeFidia Farmaceutici S.P.A.
InventorsDavide Bellini, Alessandra Topai
Estimating the term…
An amide of hyaluronic acid or a derivative thereof which comprises at least one repetitive unit of general formula (I): wherein R=NR6R7, or alcoholic group of the aliphatic, aromatic, arylaliphatic, cycloaliphatic, heterocyclic series, OH, O—, alcoholic group of hyaluronic acid, amino group of deacylated hyaluronic acid; R1, R2, R3, R4=H, SO3—, acyl group derived from a carboxylic acid of the aliphatic, aromatic, arylaliphatic, cycloaliphatic, heterocyclic series, —CO—(CH2)2—COOY; Y=negative charge, or H; R5=—CO—CH3, H, SO3—, acyl group derived from a carboxylic acid of the aliphatic, aromatic, arylaliphatic, cycloaliphatic, heterocyclic series, acylic group of hyaluronic acid; R6=is H or a aliphatic, aromatic, arylaliphatic, cycloaliphatic, or heterocyclic group, substituted or unsubstituted; R7=is H or an aliphatic, aromatic, arylaliphatic, cycloaliphatic, or heterocyclic group, substituted or unsubstituted; wherein at least one of R or R5 forms an amide group.
A pharmaceutical composition or biomaterial comprising a water-soluble amide compound of hyaluronic acid or a derivative thereof which comprises at least one repetitive unit of the following general formula:
A pharmaceutical composition or biomaterial comprising a water-soluble amide compound of hyaluronic acid or a derivative thereof which comprises at least one repetitive unit of the following general formula:
Dependencies are inferred from the claim text.