Cosmetic uses of modified stressed yeast extracts and related compositions
AssigneeAvon Products, Inc.
InventorsUma Santhanam, Christos D. Kyrou, Desiree Mazich, Qi Hong, Hussam H. Shaheen
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Abstract
Cosmetic compositions comprising a metal-complexed peptide fraction of stressed yeast extracts and/or a calcium influx inhibitor are disclosed, as well as methods of using such compositions to impart exfoliating, anti-aging, anti-lipid, anti-inflammatory, and/or lightening benefits to the skin; and/or lightening benefits to the hair. These compositions are believed to have modulatory activity against at least one biochemical pathway implicated in skin aging, inflammation, lipid synthesis, and melanin production.
Claims24
A method for treating hyper-pigmentation comprising topically applying to an area of hyper-pigmented skin a composition comprising an effective amount of a peptide comprising SEQ ID NO:1, or a homolog thereof having one or more conservative amino acid substitutions, in a cosmetically acceptable vehicle,
- wherein said peptide or homolog thereof has been modified by complexation with one or more metal ions, and
- wherein said metal-complexed peptide is present in an amount sufficient to decrease melanin synthesis in said area of hyper-pigmented skin.
A method for lightening skin or hair, comprising topically applying to said skin or hair a composition comprising an effective amount of a peptide comprising SEQ ID NO:1, or a homolog thereof having one or more conservative amino acid substitutions, in a cosmetically acceptable vehicle
- wherein said metal-complexed peptide or homolog thereof has been modified by complexation with one or more metal ions and
- wherein said metal-complexed peptide is applied for a time sufficient to lighten said skin or hair.
A method for providing a benefit to human skin comprising topically applying to skin in need thereof a composition comprising an effective amount of a peptide comprising SEQ ID NO:1, or a homolog thereof having one or more conservative amino acid substitutions, in a cosmetically acceptable vehicle, wherein said peptide or homolog thereof has been modified by complexation with one or more metal ions.
A method for treating inflammation of skin, comprising topically applying to said skin a composition comprising an effective amount of a peptide comprising SEQ ID NO:1, or a homolog thereof having one or more conservative amino acid substitutions, in a cosmetically acceptable vehicle for a time sufficient to eradicate, reduce, ameliorate;
- or reverse one or more unwanted features associated with inflammation, wherein said peptide or homolog thereof has been modified by complexation with one or more metal ions.
A topical composition comprising:
- from 0.001 weight % to 5 weight % of peptide comprising SEQ ID NO:1, or a homolog thereof having one or more conservative amino acid substitutions, in a cosmetically acceptable vehicle;
- wherein said metal-complexed peptide or homolog thereof has been modified by complexation with one or more metal ions;
- and wherein said topical composition is in the form of a lotion, cream, essence ointment, gel, or stick.
A method for treating skin lipid over-production comprising topically applying to an area of skin affected by lipid over-production a composition comprising an effective amount of a peptide comprising SEQ ID NO:1, or a homolog thereof having one or more conservative amino acid substitutions, in a cosmetically acceptable vehicle for a time sufficient to reduce said lipid over-production, wherein said peptide or homolog thereof has been modified to be in complexation with a metal ion.
A method for enhancing exfoliation comprising topically applying to an area of skin in need thereof a composition comprising an effective amount of a metal-complexed peptide comprising SEQ ID NO:1, or a homolog thereof having one or more conservative amino acid substitutions, in a cosmetically acceptable vehicle;
- and rubbing said composition against said skin to enhance exfoliation;
- wherein said metal-complexed peptide or homolog thereof has been modified by complexation with one or more metal ions.
Dependencies are inferred from the claim text.