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US 8,575,093 B2Granted
Composition and method for treating Streptococcus pneumoniae infection
AssigneesBen-Gurion University of the Negev Research and Development Authority, Mor Research Applications Ltd.
InventorsYaffa Mizrachi Nebenzahl, Ron Dagan
Life of this patent
Estimating the term…
Abstract
A method of preventing and/or treating S. pneumoniae infection in mammalian subjects, wherein said method comprises administering to said subjects a composition comprising one or more agents that are capable of inhibiting the binding of the S. pneumoniae cell wall protein FBA to the respiratory tract cells of said subject.
Claims5
A composition comprising the one or more peptides selected from the group consisting of:
- (SEQ ID NO 1)
- a) Asp-Ser-Asp-Ser-Asp-Ser-Asp-Leu-Ser-Leu-Glu-
- Olu-Glu;
- (SEQ ID NO 2)
- b) Ala-Asp-Ser-Asp-Ser-Asp-Ser-Asp-Leu-Ser-Leu-
- Glu-Glu-Glu-Arg.
3 more elements
An isolated peptide consisting of the following sequence:
- (SEQ ID NO:
- 1)
- Asp-Ser-Asp-Ser-Asp-Ser-Asp-Leu-Ser-Leu-Glu-
- Glu-Glu.
1 more element
An isolated peptide of consisting the following sequence:
- (SEQ ID NO:
- 2)
- Ala-Asp-Ser-Asp-Ser-Asp-Ser-Asp-Leu-Ser-Leu-
- Glu-Glu-Glu-Arg.
1 more element
Dependencies are inferred from the claim text.