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US 8,575,090 B2Granted
Amylin analogues and pharmaceutical compositions thereof
AssigneeNovo Nordisk A/S
InventorsLauge Schaeffer, Thomas Kruse, Henning Thoegersen
Life of this patent
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Abstract
The invention relates to polypeptides comprising an amino acid sequence which is an analogue of pramlintide, pharmaceutical compositions comprising these polypeptides, and these polypeptides for use as medicaments.
Claims11
A polypeptide comprising an amino acid sequence which is an analogue of SEQ ID No:
- 2 wherein:
- said analogue comprises a proline residue at position 37, a glutamic acid at position 14 and an arginine at position 17;
- wherein the amino acid sequence numbering of the analogue corresponds to the amino acid numbering sequence of SEQ ID No:
- 2.
1 more element
Dependencies are inferred from the claim text.