Cryoconserved mature dendritic cells
AssigneeArgos Therapeutics, Inc.
InventorsGerold Schuler, Beatrice Schuler-Thurner
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Abstract
The invention relates to a method for producing ready to use, antigen loaded or unloaded, cryoconserved mature dendritic cells especially for the production of a vaccine containing said dendritic cells, wherein immature dendritic cells are cultivated in the presence of suitable maturation stimuli and the mature dendritic cells thus obtained are frozen. The dendritic cells can be loaded with antigen before freezing. The invention also relates to a vaccine which can be obtained according to the inventive method and to a composition containing frozen, mature dendritic cells which are loaded with antigen.
Claims10
Mature dendritic cells frozen in freezing medium comprising autologous serum, 5-25% DMSO, and 5-10% glucose.
Dependencies are inferred from the claim text.