Method for preparing a biocomposite comprising one or more enzymes
AssigneeDanisco US Inc.
InventorsRisha Bond, Michael C. Jewett, Joseph C. McAuliffe, Donald E. Ward, II
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AssigneeDanisco US Inc.
InventorsRisha Bond, Michael C. Jewett, Joseph C. McAuliffe, Donald E. Ward, II
Estimating the term…
This invention relates to a method of immobilizing biocatalysts including protein and cells by co-precipitation with silicate or organosilicate matrices through the action of an organic template molecule. The organic template molecule is in general a polyamine such as polyethylenimine (PEI), or polypeptide compound bearing at least two or three basic residues selected from the group consisting of lysine, arginine, histidine, proline, hydroxyproline, N-methylhistidine, ornithine, taurine, δ-hydroxylysine, and δ-hydroxy-ω-N,N,N trimethyllysine. The invention is also directed to a silica biocomposite comprising co-precipitates of active biocatalysts, silica or organosilicates, and an N-containing organic template molecule. Such silica biocomposites are useful in biocatalysis, and other applications requiring an immobilized biocatalyst. Preferred biocatalysts for this invention are enzymes and whole cells.
A method for preparing a biocomposite comprising one or more enzymes comprising the steps of:
Dependencies are inferred from the claim text.