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US 8,574,866 B2Granted
Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
AssigneeUniversity of South Florida
InventorMatt Ewert
Life of this patent
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Abstract
The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
Claims16
A method of permitting pathogen capture from a biological sample, the method comprising:
- a. contacting the sample with aurintricarboxylic acid (ATA), a DNase, and an enzyme that will break down a nuclear membrane.
Dependencies are inferred from the claim text.