Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
AssigneepSivida US, Inc.
InventorsHong Guo, Paul Ashton
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Abstract
A method and device for treating a mammalian organism to obtain a desired local or systemic physiological or pharmacological effect is provided. The method includes administering a sustained release drug delivery system to a mammalian organism in need of such treatment at an area wherein release of an effective agent is desired and allowing the effective agent to pass through the device in a controlled manner. The device includes an inner core or reservoir including the effective agent, an impermeable tube which encloses portions of the reservoir, and a permeable member at an end of the tube.
Claims6
A method of manufacturing a sustained drug delivery system, comprising
- positioning a drug core in an impermeable tube, said drug core containing a therapeutically effective amount of an active agent, wherein said impermeable tube is dimensionally stable and capable of supporting its own weight;
- cross-sectionally cutting the tube into sections;
- and
- forming a permeable outer layer around at least a portion of a section.
Dependencies are inferred from the claim text.