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US 8,574,629 B2Granted
Injectable hydrogel with an enhanced remanence and with an enhanced ability to create volume
AssigneeAnteis S.A.
InventorSamuel Gavard Molliard
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Abstract
An injectable hydrogel includes a hydrogel matrix based on (a) single-phase-type cross-linked biopolymer(s), characterized in that previously cross-linked biopolymer hydrogel particles are co-cross-linked with the matrix. A method of and a process for production of the above-mentioned hydrogel are also disclosed.
Claims18
An injectable hydrogel that comprises:
- a hydrogel matrix comprising single phase cross-linked biopolymer(s), and
- previously cross-linked biopolymer hydrogel particles co-cross-linked with said matrix,
- wherein the biopolymer(s) is (are) selected from the group consisting of sodium hyaluronate, chondroitin sulfate, keratan, keratan sulfate, heparin, heparan sulfate, cellulose and its derivatives, alginates, xanthan, carrageenan, proteins, nucleic acids and mixtures thereof,
- the total biopolymer concentration is between 0.01 and 100 mg/ml,
- the mass percent of particles in the single-phase matrix is between 1 and 99%, and
- the particles have an inside diameter of between 50 and 1000 micrometers.
3 more elements
Dependencies are inferred from the claim text.