Therapeutic agent for pulmonary fibrosis
AssigneeNitto Denko Corporation
InventorsYoshiro Niitsu, Rishu Takimoto, Kenjiro Minomi, Miyono Miyazaki, Keiko Kajiwara, Yasunobu Tanaka
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Abstract
Disclosed are: a substance transfer carrier to an extracellular matrix-producing cell in the lung, which comprises a retinoid; a therapeutic agent for pulmonary fibrosis, which utilized the carrier; and a preparation kit of the therapeutic agent.
Claims6
A composition for treating pulmonary fibrosis, comprising a substance delivery carrier that comprises an amount of a retinoid targeting agent that is effective to specifically target the substance delivery carrier to extracellular matrix-producing cells in the lung and a drug that controls the activity or growth of extracellular matrix-producing cells in the lung, wherein the drug that controls the activity or growth of extracellular matrix-producing cells in the lung is selected from the group consisting of an siRNA, a ribozyme, an anti-sense nucleic acid, and a DNA/RNA chimeric polynucleotide which target HSP47.
Dependencies are inferred from the claim text.