Pharmaceutical composition of nanoparticles
AssigneesGP Medical, Inc., National Tsing Hua University
InventorsHsing-Wen Sung, Ha Giang Thi Nguyen, Fang Yi Su, Er-Yuan Chuang, Zi-Xian Liao, Hosheng Tu
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Abstract
The invention discloses a pharmaceutical composition of nanoparticles consisting of chitosan, a negatively charged substrate, and at least one bioactive agent that is encapsulated within cucurbiturils for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.
Claims20
A composition of nanoparticles, said nanoparticles consisting of a shell portion that is dominated by positively charged chitosan, a core portion that consists of said positively charged chitosan, one negatively charged substrate, and optionally a zero-charge compound or at least one bioactive agent that is encapsulated within cucurbiturils.
Dependencies are inferred from the claim text.