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US 8,574,433 B2Granted
Ion exchange porous resins for solid phase extraction and chromatography
AssigneeWaters Technologies Corporation
InventorsPeter Jeng-Jong Lee, John E. O'Gara
Life of this patent
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Abstract
Embodiments of the present invention are directed to porous resins for solid phase extractions. The resins feature at least one hydrophobic component, at least one hydrophilic component and at least one ion exchange functional group. The resins exhibit superior wetting and ion exchange performance.
Claims12
A porous resin for solid phase extraction or chromatography, wherein said porous resin is a compound of formula I:
- -(A)n-(B)m—(C)p— (I)
- and salts thereof,
- wherein the order of A, B and C may be random, block, or a combination of random and block;
- wherein
- 1
- 100
- <
- (
- p
- +
- n
- )
- m
- <
- 100
- 1
- and
- 1
- 500
- <
- p
- n
- <
- 100
- 1
- ;
- wherein A is selected from the group consisting of
- wherein B is selected from the group consisting of
- wherein C is A or modified A, wherein modified A is selected from the group consisting of
- and
- wherein X is selected from the group consisting of SO3H, CH2CO2H, CH2CH(CO2H)2, CO2H, PO3H2, PO2H2, CH2PO3H2, CH2Cl, CH2NH2,
- CH2N[(CH2)yCH3]2 wherein y is any integer from 0 to 18, CH2N+[(CH2)yCH3]3D− wherein y′ is any integer from 0 to 18 and D− is an anion, SO2NHR wherein R is polyethylenimine, and CH2NHR wherein R is polyethylenimine;
- and wherein X is present at a concentration of about 0.6 to about 3.2 milliequivalents per gram of resin.
30 more elements
Dependencies are inferred from the claim text.