Back to results
US 8,574,292 B2Granted
Ophthalmic and otorhinolaryngological device materials containing an alkylphenol ethoxylate
AssigneeNovartis AG
InventorsWater R. Laredo, Douglas C. Schlueter
Life of this patent
Estimating the term…
Abstract
Disclosed are soft, high refractive index, acrylic device materials. The materials contain a functionalized alkylphenol ethoxylate to reduce glistenings.
Claims12
An ophthalmic or otorhinolaryngological device selected from the group consisting of intraocular lenses;
- contact lenses;
- keratoprostheses;
- corneal inlays or rings;
- otological ventilation tubes;
- and nasal implants, wherein the device comprises a copolymeric ophthalmic or otorhinolaryngological device material formed by polymerizing a composition comprising
- a) 75 to 97% (w/w) of a monofunctional acrylate or methacrylate monomer of formula [1]:
- wherein
- B═O(CH2)n, NH(CH2)n, or NCH3(CH2)n;
- R1═H, CH3, CH2CH3, or CH2OH;
- n=0-12;
- A=C6H5 or O(CH2)mC6H5, where the C6H5 group is optionally substituted with —(CH2)nH, —O(CH2)H, —CH(CH3)2, —C6H5, —OC6H5, —CH2C6H5, F, Cl, Br, or I;
- and
- m=0-22;
- b) a difunctional acrylate or methacrylate cross-linking monomer of formula [2]:
- wherein
- R2, R3 independently=H, CH3, CH2CH3, or CH2OH;
- W, W′ independently=O(CH2)d, NH(CH2)d, NCH3(CH2)d, O(CH2)dC6H4, O(CH2CH2O)dCH2, O(CH2CH2CH2O)dCH2, O(CH2CH2CH2CH2O)dCH2, or nothing;
- J=(CH2)a, O(CH2CH2O)b, O, or nothing, provided that if W and W′=nothing, then J≠nothing;
- d=0-12;
- a=1-12;
- and
- b=1-24;
- and
- c) 3% (w/w) of an alkylphenol ethoxylate monomer of formula [3]:
- wherein:
- T=C8H17 or C9H19;
- e=40;
- or
- R4=H, CH3 and CH2CH3
- provided that the device material has a glass transition temperature not greater than 25° C.
27 more elements
Dependencies are inferred from the claim text.