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US 8,574,259 B2Granted
Intravascular filter with drug reservoir
AssigneeLifescreen Sciences LLC
InventorsEric D. Welch, Timothy S. Girton, Joel M. WasDyke
Life of this patent
Estimating the term…
Abstract
An intravascular filter can capture and eliminate emboli. In particular, an intravascular filter may include a plurality of filter legs extending from an apical head. The filter legs may be configured to capture emboli. A drug reservoir that includes or contains a therapeutic drug can be disposed near the apical head. The therapeutic drug, such as a thrombolytic or anti-coagulatory drug, may be eluted in response to a captured emboli.
Claims11
An intravascular filter, comprising:
- a plurality of filter legs, each of the filter legs having a free end and an opposite joined end;
- an apical head, the joined end of each of the filter legs secured to the apical head, each of the filter legs radiating outwardly from the apical head;
- and
- a drug reservoir disposed near the apical head, the drug reservoir comprising a drug dispersed only within poly(styrene-b-isobutylene-b-styrene), wherein the drug reservoir comprises a cup having a hollow volume positioned inside the plurality of filter legs, the cup having an open end and a closed end, where the closed end is positioned closest to the apical head while the open end extends away from the apical head.
1 more element
A method of dissolving embolic debris within a vasculature, comprising steps of:
- providing an intravascular filter having an apical head and a drug reservoir positioned at or near the apical head, the drug reservoir comprising a thrombolytic drug dispersed only within poly(styrene-b-isobutylene-b-styrene), wherein the drug reservoir comprises a cup having a hollow volume positioned inside the plurality of filter legs, the cup having an open end and a closed end, where the closed end is positioned closest to the apical head while the open end extends away from the apical head;
- deploying the intravascular filter within the vasculature;
- and
- eluting a thrombolytic drug from the drug reservoir in response to an emboli contacting the drug reservoir, thereby dissolving the embolic debris.
1 more element
Dependencies are inferred from the claim text.