Implantable arterio-venous shunt devices and methods for their use
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsJohn Faul, Toshihiko Nishimura, Peter Kao, Ronald Pearl
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AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsJohn Faul, Toshihiko Nishimura, Peter Kao, Ronald Pearl
Estimating the term…
A long-term implantable arterio-venous shunt device or creation of a fistula is provided that can be used as a therapeutic method for treating chronic obstructive pulmonary disease (COPD). The shunt device is implanted between an artery and a vein, preferably between a peripheral artery and the inferior vena cava. The shunt device and method of creating a fistula increases cardiac output and decreases the systemic vascular resistance and allows a blood flow rate through the shunt device of at least 5 ml/min after the implantation. Based on the effects of the method and device to the respiratory, cardiac and circulatory system, the method and device are beneficial as a therapy to patients with problems or conditions related to these systems.
A therapeutic method for increasing cardiac output in a human subject, the method comprising:
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