Method for characterizing particles in liquid using a dual sample cartridge
AssigneeKoninklijke Philips N.V.
InventorUlrik Darling Larsen
Life of this patent
Estimating the term…
Abstract
A method for characterizing particles suspended in a liquid, in a self-contained disposable cartridge for single-use analysis, such as for single-use analysis of a small quantity of whole blood. The method characterizes particles in liquid and samples a small and accurate volume of liquid. The cartridge includes a housing having a mixing chamber and a collection chamber separated by a wall containing an opening, a first bore in the outer surface of the housing for entrance of a liquid sample, a first cavity for receiving and holding a first liquid sample, and a second cavity for receiving and holding a second liquid sample.
Claims18
A method for characterizing particles in liquid, comprising the steps of:
- a) entering first and second liquid samples containing particles for simultaneous holding in respective first and second cavities,
- b) moving first liquid through the first cavity and into a mixing chamber her with the first liquid sample,
- c) performing first particle characterizing measurements by passage of at least a part of the first liquid sample from the mixing chamber through an opening and into a collection chamber,
- d) moving second liquid through the second cavity and into the mixing chamber together with the second liquid sample, and
- e) performing second particle characterizing measurements by passage of at least a part of the second liquid sample from the mixing chamber through the opening and into the collection chamber,
- wherein the first and second cavities are disposed in respective rotatable first and second sampling members.
A method for characterizing particles in liquid, comprising the steps of:
- a) entering first and second liquid samples containing particles for simultaneous holding in respective first and second cavities,
- b) moving first liquid through the first cavity and into a mixing chamber together with the first liquid sample,
- c) performing first particle characterizing measurements by passage of at least a part of the first liquid sample from the mixing chamber through an opening and into a collection chamber,
- d) moving second liquid through the second cavity and into the mixing chamber together with the second liquid sample, and
- e) performing second particle characterizing measurements by passage of at least a part of the second liquid sample from the mixing chamber through the opening and into the collection chamber,
- wherein the first and second cavities are disposed in a rotatable sampling member.
A method for characterizing particles in liquid, comprising:
- entering first and second liquid samples containing particles respectively into first and second cavities;
- changing a position of the first cavity to move a first liquid through the first cavity and into a mixing chamber together with the first liquid sample;
- performing first particle characterizing measurements by passage of at least a part of the first liquid sample from the mixing chamber through an opening and into a collection chamber;
- changing a position of the second cavity to move a second liquid through the second cavity and into the mixing chamber together with the second liquid sample;
- and
- performing second particle characterizing measurements by passage of at least a part of the second liquid sample from the mixing chamber through the opening and into the collection chamber,
- wherein the first and second cavities are disposed in respective rotatable first and second sampling members;
- and
- wherein said entering first and second liquid samples comprises moving the first and second sample members to respective first positions so that the first and second cavities are in flow communication with each other.
A method for characterizing particles in liquid, comprising:
- entering first and second liquid samples containing particles respectively into first and second cavities;
- changing a position of the first cavity to move a first liquid through the first cavity and into a mixing chamber together with the first liquid sample;
- performing first particle characterizing measurements by passage of at least a part of the first liquid sample from the mixing chamber through an opening and into a collection chamber;
- changing a position of the second cavity to move a second liquid through the second cavity and into the mixing chamber together with the second liquid sample;
- and
- performing second particle characterizing measurements by passage of at least a part of the second liquid sample from the mixing chamber through the opening and into the collection chamber,
- wherein the first and second cavities are disposed in a rotatable sampling member, and
- wherein said entering first and second liquid samples comprises moving the sample member to a first position so that the first and second cavities are in flow communication with each other.
Dependencies are inferred from the claim text.