Method to diagnose and measure vascular drainage insufficiency in the central nervous system
OwnerDavid R. Hubbardinventor
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OwnerDavid R. Hubbardinventor
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Neurodegenerative diseases, such as multiple sclerosis, may be caused or aggravated by insufficient venous draining from the central nervous system. Functional MRI measures the surge of blood flow into localized regions of cerebral cortex in response to activation of those regions by performing visual, auditory or executive tasks. These fMRI measurements are based on blood-oxygen-level dependence. The resulting fMRI/BOLD data is converted to hemodynamic response data and analyzed to determine any abnormality in the hemodynamic response data. Vascular drainage insufficiency is identified in the presence of abnormal hemodynamic response data. Abnormal hemodynamic response data can be determined by a negative trough in a graph of the HDR data or by the duration, depth, or area of the negative trough.
A functional magnetic resonance scanner apparatus comprising at least one processor communicatively coupled with at least one non-transitory computer readable medium, wherein the processor is programmed to:
A technical system for identifying vascular drainage insufficiency in the central nervous system, the system comprising:
A computer implemented method for identifying vascular drainage insufficiency in the central nervous system, comprising:
A non-transitory computer readable medium having stored thereon one or more sequences of instructions for causing one or more processors to perform the steps for identifying vascular drainage insufficiency in the central nervous system, the steps comprising:
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