# US 8,570,511 B2 · Wide size range fast integrated mobility spectrometer

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- Number: US 8,570,511 B2
- Document ID: US8570511B2
- Status: Granted
- Kind: B2
- Application number: 12/877,677
- Filed: 2010-09-08
- Published: 2011-05-19
- Granted: 2013-10-29
- Earliest claimed: 2009-09-09
- Assignees: Brookhaven Science Associates, LLC
- Applicants: Jian Wang
- Inventors: Jian Wang
- Web page: https://patentgrep.com/patent/US8570511B2

## CPC

- G01N 15/0266: {with electrical classification}
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)

## Abstract

A mobility spectrometer to measure a nanometer particle size distribution is disclosed. The mobility spectrometer includes a conduit and a detector. The conduit is configured to receive and provide fluid communication of a fluid stream having a charged nanometer particle mixture. The conduit includes a separator section configured to generate an electrical field of two dimensions transverse to a dimension associated with the flow of the charged nanometer particle mixture through the separator section to spatially separate charged nanometer particles of the charged nanometer particle mixture in said two dimensions. The detector is disposed downstream of the conduit to detect concentration and position of the spatially-separated nanometer particles.

## Claims

### Claim 1

A mobility spectrometer to measure a nanometer particle size distribution, said mobility spectrometer comprising:
a conduit configured to receive and provide fluid communication of a fluid stream having a charged nanometer particle mixture, said conduit including:
a separator section configured to generate an electrical field in two dimensions transverse to a dimension associated with the flow of said charged nanometer particle mixture through said separator section to spatially separate charged nanometer particles of said charged nanometer particle mixture within said two dimensions and where said electrical field along said separator section is non-uniform in at least a first dimension of said two transverse dimensions; and
a detector disposed downstream of said conduit to detect said spatially-separated nanometer particles.

### Claim 2 (depends on 1)

The mobility spectrometer of claim 1, wherein said conduit further includes:
a condenser section located between said separator section and said detector configured to condense a condensing agent added to said charged nanometer particle mixture and to grow said spatially-separated nanometer particles.

### Claim 3 (depends on 2)

The mobility spectrometer of claim 2, wherein said condenser section is electrically insulated from said separator section.

### Claim 4 (depends on 2)

The mobility spectrometer of claim 2, wherein said detector is a camera disposed downstream of said conduit configured to capture images of said grown spatially-separated nanometer particles.

### Claim 5 (depends on 1)

The mobility spectrometer of claim 1, wherein said separator section includes:
a first wall having a first electrode extending along said first wall; and
a second opposing wall having a second electrode extending along said second opposing wall, said second electrode comprising a plurality of electrical elements configured to generate said electrical field in two dimensions transverse to the dimension associated with the flow of said charged nanometer particle mixture.

### Claim 6 (depends on 5)

The mobility spectrometer of claim 5, wherein said transverse electrical field is non-uniform in both transverse dimensions.

### Claim 7 (depends on 5)

The mobility spectrometer of claim 5, wherein said plurality of electrical elements further include at least:
a first electrical element extending along said second opposing wall and set to a first voltage; and
a second electrical element extending along said second opposing wall at a distance separated from said first electrical element and set to a second voltage sufficiently different from said first voltage to generate said transverse electrical field.

### Claim 8 (depends on 7)

The mobility spectrometer of claim 7, wherein said plurality of electrical elements further include at least:
a third electrical element extending along said second opposing wall at a distance separated from others of said electrical elements and set to a voltage appropriate to enhance said transverse electrical field.

### Claim 9 (depends on 8)

The mobility spectrometer of claim 8, wherein said plurality of electrical elements are set to linearly or exponentially varying voltages between said first voltage and said second voltage.

### Claim 10

A mobility spectrometer system to measure a nanometer particle size distribution, said mobility spectrometer system comprising:
a charger configured to receive a first fluid stream of nanometer particles and to charge said nanometer particles, said charger further configured to direct said first fluid stream of charged nanometer particles into a conduit of a mobility spectrometer;
a mobility spectrometer in fluid communication with said charger, said mobility spectrometer comprising:
a conduit configured to receive and provide fluid communication of at least said first fluid stream, said conduit including:
a separator section configured to generate an electrical field in two dimensions transverse to a dimension associated with the flow of said first fluid stream through said separator section to spatially separate charged nanometer particles of said first fluid stream in said two dimensions and where said electrical field over said separator section is non-uniform in at least a first dimension of said two transverse dimensions; and
a detector disposed downstream of said conduit to detect said spatially-separated nanometer particles.

### Claim 11 (depends on 10)

The mobility spectrometer system claim 10, wherein said mobility spectrometer system further comprises:
a saturator configured to saturate a second fluid stream with a condensing agent and to direct said second fluid stream into said conduit of said mobility spectrometer.

### Claim 12 (depends on 11)

The mobility spectrometer system claim 11, wherein said mobility spectrometer further comprises:
a condenser section configured to condense said condensing agent and to grow said spatially-separated nanometer particles.

### Claim 13 (depends on 12)

The mobility spectrometer system claim 12, wherein said separator section is electrically insulated from said a condenser section.

### Claim 14 (depends on 12)

The mobility spectrometer system of claim 12, wherein said detector is a camera disposed downstream of said conduit configured to capture images of said grown spatially-separated nanometer particles.

### Claim 15 (depends on 10)

The mobility spectrometer system of claim 10, wherein said separator section includes:
a first wall having a first electrode extending along said first wall; and
a second opposing wall having a second electrode extending along said second opposing wall, said second electrode comprising a plurality of electrical elements configured to generate said electrical field in two dimensions transverse to the dimensions associated with the flow of said first fluid stream.

### Claim 16 (depends on 15)

The mobility spectrometer system of claim 15, wherein said transverse electrical field is non-uniform in both transverse dimensions.

### Claim 17 (depends on 15)

The mobility spectrometer system of claim 15, wherein said plurality of electrical elements further include at least:
a first electrical element extending along said second opposing wall and set to a first voltage; and
a second electrical element extending along said second opposing wall at a distance separated from said first electrical element and set to a second voltage sufficiently different from said first voltage to generate said transverse electrical field.

### Claim 18 (depends on 17)

The mobility spectrometer system of claim 17, wherein said plurality of electrical elements further include at least:
a third electrical element extending along said second opposing wall at a distance separated from others of said electrical elements and set to a voltage appropriate to enhance said electrical field.

### Claim 19 (depends on 18)

The mobility spectrometer system of claim 18, wherein said plurality of electrical elements are set at linearly or exponentially varying voltages between said first voltage and said second voltage.

### Claim 20 (depends on 10)

The mobility spectrometer system of claim 10, further comprising a computing device operably connected to said detector, said computing device configured to determine concentration and position of said spatially-separated nanometer particles.

### Claim 21

A method of measuring a nanometer particle size distribution, the method comprising:
flowing a fluid stream having a charged nanometer particle mixture through a conduit of a mobility spectrometer, the conduit including at least a separator section;
applying a transverse non-uniform electrical field in the separator section in at least one of two dimensions transverse to a dimension associated with the flow of the charged nanometer particle mixture through the separator section to spatially separate the charged nanometer particles within the two dimensions;
detecting the spatially-separated nanometer particles.

### Claim 22 (depends on 21)

The method of claim 21, further comprising flowing a first fluid stream having a nanometer particle mixture through a charging zone which charges the particles of the nanometer particle mixture and directs the first fluid stream into the conduit of the mobility spectrometer.

### Claim 23 (depends on 21)

The method of claim 21, further comprising flowing a second fluid stream through a saturation zone that saturates the second fluid stream with a condensing agent and directs the second fluid stream into the conduit of the mobility spectrometer.

### Claim 24 (depends on 23)

The method of claim 23, further comprising growing the spatially-separated nanometer particles by condensing the condensing agent in a condenser section of the conduit.

### Claim 25 (depends on 24)

The method of claim 24, wherein detecting includes:
illuminating the grown spatially-separated nanometer particles; and
capturing images of the grown spatially-separated nanometer particles.

### Claim 26 (depends on 21)

The method of claim 21, wherein applying the transverse electrical field further comprises:
grounding a first electrode of the separator section, the first electrode extending along a first wall of the separator; and
applying varying voltages to a plurality of electrical elements of a second electrode of the separator section to generate the transverse electrical field in two dimensions, the second electrode extending along a second opposing wall of the separator section.

### Claim 27 (depends on 26)

The method of claim 26, wherein the applying varying voltages to the plurality of electrical elements of the second electrode comprises applying different voltages to different electrical elements of the plurality of electrical elements, including at least:
applying a first voltage to a first electrical element of the second electrode extending along the second opposing wall; and
applying a second voltage sufficiently different from the first voltage to generate the transverse electrical field to a second electrical element of the second electrode disposed at a distance separated from the first electrical element and extending along the second opposing wall.

### Claim 28 (depends on 27)

The method of claim 27, wherein the applying varying voltages to the plurality of electrical elements of a second electrode further includes:
applying a voltage appropriate to enhance the transverse electrical field to at least a third electrical element of the second electrode extending along the second opposing wall.

### Claim 29 (depends on 28)

The method of claim 28, wherein the applying varying voltages further includes:
applying a plurality of different voltages to a plurality of different electrical elements of the second electrode, the voltages varying linearly or exponentially between the first voltage and the second voltage.

### Claim 30 (depends on 21)

The method of claim 21, further comprising determining the concentration and position of the spatially-separated nanometer particles.
