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US 8,569,367 B2Granted
Ophthalmic compositions and methods for treating eyes
AssigneeAllergan, Inc.
InventorsJoseph G. Vehige, Peter A. Simmons, Joan-En Chang-Lin
Life of this patent
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Abstract
Ophthalmic compositions including compatible solute components and/or polyanionic components are useful in treating eyes, for example, to relieve dry eye syndrome, to protect the eyes against hypertonic insult and/or the adverse effects of cationic species on the ocular surfaces of eyes and/or to facilitate recovery from eye surgery.
Claims18
A topical ophthalmic composition for the treatment of dry eye comprising:
- an aqueous carrier;
- erythritol, its isomers or suitable salts thereof;
- carnitine, its isomers or suitable salts thereof;
- and
- an ionically charged polymeric material selected from the group consisting of carboxymethyl cellulose and mixtures of carboxymethyl cellulose compounds;
- and
- wherein the composition is effective for the treatment of dry eye.
4 more elements
An artificial tear for treating dry eye by providing osmoprotection to the ocular surface comprising:
- erythritol, its isomers or suitable salts thereof;
- carnitine, its isomers or suitable salts thereof;
- carboxymethylcellulose;
- and
- water;
- and
- wherein the composition is effective for the treatment of dry eye.
4 more elements
An ophthalmically acceptable composition comprising:
- carnitine, or a stereoisomer or a salt thereof;
- erythritol, or a stereoisomer thereof, in an amount that is effective to treat dry eye;
- an anionic cellulose derivative in an amount that is effective to treat dry eye;
- a tonicity adjusting component that is not erythritol;
- and
- water.
3 more elements
Dependencies are inferred from the claim text.