Bicyclic urea compounds

A compound of Formula (I):

• or a pharmaceutically acceptable salt thereof, wherein:
• X is a bond, NH, O, S, or CH2NH or CH2O, wherein NH or O moieties are connected to the 2-oxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine moiety,
• Q is a 5- or 6-membered monocyclic, or 9- or 10-membered bycyclic, aromatic, homo- or heterocycle having 1 or 2 N, O and/or S atoms, which may be unsubstituted or, independently of one another, mono- or disubstituted by Hal, LA, C(Hal)3, OC(Hal)3, OH, SH, O(LA), NH2, NH(LA), N(LA)2, NO2, CN, OCN, 4-fluorophenyl, oxo or SCN,
• M is a bond, CH2, CO, SO2, CONH, NHCO, NHCONH, SO2NH, NHSO2, NHSO2NH or CH2NHCO, wherein the CO moiety is connected to Q,
• R1 is H, A, Ar or Ar-A,
• R2 is H, or
• R1 and R2 together with the N and C atoms to which they are attached, may form a 5- or 6-membered aliphatic heterocycle having 1 or 2 N, O and/or S atoms, which may be unsubstituted or substituted by Hal, A, OH, NH2 or CN,
• R3 is A or Q, or
• R3-M may be absent,
• Ar is a mono- or bicyclic aromatic homo- or heterocycle having 1 to 4 N, O and/or S atoms and 5to 10 skeleton atoms, which may be unsubstituted or, independently of one another, mono-, di- or trisubstituted by Hal, A, OH, SH, OA, NH2, NHA, NA2, NO2, CN, OCN, SCN, COOH, COOA, CONH2, CONHA, CONH(LAr), CONA2, NHCOA, NHCO(LAr), NHCONHA, NHCONH2, NHSO2A, CHO, COA, SO2NH2, SO2A and/or SO2Hal,
• A is unbranched or branched, linear or cyclic alkyl having 1, 2, 3, 4, 5, 6, 7 or 8 C atoms, in which one or two CH2 groups may be replaced by an O or S atom and/or by an NH, CO, N(LA), SO2, CONH, NHCO or —CH═CH—group, and in which 1-3 H atoms may be replaced by Hal, and in which one or two CH3 groups may be replaced by OH, SH, NH2, NH(LA), N(LA)2, NHCOOH, NHCONH2, N3, NO2 or CN,
• LA is unbranched or branched, linear alkyl having 1, 2, 3 or 4 C atoms,
• Hal is F, Cl, Br or I.