Diphenyl sulfide derivatives and medicines containing same as active ingredient
AssigneeKyorin Pharmaceutical Co., Ltd.
InventorsYasushi Kohno, Kiyoshi Fujii, Momoko Taru, Keita Miyoshi
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AssigneeKyorin Pharmaceutical Co., Ltd.
InventorsYasushi Kohno, Kiyoshi Fujii, Momoko Taru, Keita Miyoshi
Estimating the term…
Provided are diphenyl sulfide derivatives which have excellent S1P3 antagonistic activity and are useful as drugs. Intensive studies have been made for the purpose of creating a compound having S1P3 antagonistic activity. As a result of the intensive studies, it has been found that diphenyl sulfide derivatives represented by general formula (1) have excellent S1P3 antagonistic activity. In general formula (1), R1 is a hydrogen atom or the like; R2 is an optionally substituted alkyl group having 1 to 6 carbon atoms, or the like; X is a methylene group which may be substituted with one or two fluorine atoms, or the like; Y is a hydrogen atom or the like; and Z is a halogen atom.
A diphenyl sulfide compound, or a pharmaceutically acceptable salt or hydrate thereof, represented by formula (1),
Dependencies are inferred from the claim text.