Transformant having an increased frequency of homologous recombination

An Aspergillus sojae or Aspergillus oryzae transformant having an increased frequency of homologous recombination due to suppression, via disruption or antisense, of an Aspergillus sojae or Aspergillus oryzae ku70 gene or an Aspergillus sojae or Aspergillus oryzae ku80 gene, wherein:

• the Aspergillus sojae ku70 gene comprises the DNA sequence of SEQ. ID. NO:
• 1 or encodes a protein comprising the sequence of SEQ. ID. NO:
• 2;
• the Aspergillus sojae ku80 gene comprises the DNA sequence of SEQ. ID. NO:
• 3 or encodes a protein comprising the sequence of SEQ. ID. NO:
• 4;
• the Aspergillus sojae ku80 gene comprises the DNA sequence of SEQ. ID. NO:
• 5 or encodes a protein comprising the sequence of SEQ. ID. NO:
• 6;
• the Aspergillus oryzae ku70 gene comprises the DNA sequence of SEQ. ID. NO:
• 7 or encodes a protein comprising the sequence of SEQ. ID. NO:
• 8;
• the Aspergillus oryzae ku80 gene comprises the DNA sequence of SEQ. ID. NO:
• 9 or encodes a protein comprising the sequence of SEQ. ID. NO:
• 10;
• or
• the Aspergillus oryzae ku80 gene comprises the DNA sequence of SEQ. ID. NO:
• 11;
• or encodes a protein comprising the sequence of SEQ. ID. NO:
• 12;
• wherein the frequency of homologous recombination of the Aspergillus sojae or Aspergillus oryzae transformant having the ku70 or ku80 gene suppressed via disruption is increased by at least 60 times in comparison to an Aspergillus sojae or Aspergillus oryzae strain which has not had the ku70 or ku80 gene suppressed, and the frequency of homologous recombination of the Aspergillus sojae or Aspergillus oryzae transformant having the ku70 or ku80 gene suppressed via antisense is increased by at least 10 times in comparison to an Aspergillus sojae or Aspergillus oryzae strain which has not had the ku70 or ku80 gene suppressed.