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US 8,569,000 B2Granted
Immunoassays using antibodies specific to carbamazepine
AssigneeGuangzhou Kingmed Center for Clinical Laboratory
InventorsLiuming Yu, Yaoming Liang, Hongbo Li
Life of this patent
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Abstract
The present disclosure is directed to antibodies specific to carbamazepine, immunogens used to produce the antibodies, and immunoassay kits and methods for using the antibodies.
Claims12
A method for determining the presence or absence of carbamazepine in a sample, comprising:
- (a) exposing a sample to a mixture of a labeled conjugate and an antibody specific to carbamazepine, the antibody being prepared against an immunogen;
- and
- (b) causing carbamazepine in the sample and the labeled conjugate to bind with the antibody and thereafter measuring the amount of the labeled conjugate in the mixture that is bound or unbound to the antibody, whereby the presence or absence of carbamazepine in the sample can be determined,
- wherein the immunogen and the labeled conjugate have the structure:
- wherein R is —O—(CH2)4—CO— and the carrier is an immunogenic carrier material in case of the immunogen and a detectable label in case of the labeled conjugate.
2 more elements
A method for determining the concentration of carbamazepine in a sample, comprising:
- (a) exposing a sample to a mixture of a labeled conjugate and an antibody specific to carbamazepine, the antibody being prepared against an immunogen;
- and
- (b) causing carbamazepine in the sample and the labeled conjugate to bind with the antibody and thereafter measuring the amount of the labeled conjugate in the mixture that is bound or unbound to the antibody, whereby the concentration of carbamazepine in the sample can be determined,
- wherein the immunogen and the labeled conjugate have the structure:
- wherein R is —O—(CH2)4—CO— and the carrier is an immunogenic carrier material in case of the immunogen and a detectable label in case of the labeled conjugate.
2 more elements
Dependencies are inferred from the claim text.