Isolation of a dual COX-2 and 5-lipoxygenase inhibitor from acacia
AssigneeUnigen, Inc.
InventorsQi Jia, Timothy C. Nichols, Eric E. Rhoden, Scott Waite
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Abstract
The present disclosure provides compositions and methods for alleviating inflammatory-associated diseases and conditions. These methods include administering individual and/or a mixture of multiple flavans isolated from a single or multiple Acacia genus of plants. The present disclosure also includes methods for isolating and purifying from an Acacia genus of plants a composition of flavans having dual specificity for cyclooxygenase (COX-2) and 5-lipoxygenase (5-LO) enzymes.
Claims18
A method for alleviating pain, comprising administering to a human or animal in need thereof a therapeutically effective amount of an Acacia extract enriched for catechin and epicatechin, wherein the method alleviates cyclooxygenase and 5-lipoxygenase mediated inflammation in the human or animal.
A method for improving joint comfort, comprising administering to a human or animal in need thereof an effective amount of an Acacia extract enriched for catechin and epicatechin, wherein the method alleviates cyclooxygenase and 5-lipoxygenase mediated inflammation in the human or animal.
Dependencies are inferred from the claim text.