Treatment of endothelial dysfunction in diabetic patients
AssigneeCSL Limited
InventorErik S. G. Stroes
Life of this patent
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Abstract
A method for the treatment of endothelial dysfunction in a diabetic patient, including both diabetes induced macrovascular disorders and diabetes induced microvascular disorders, comprises administration, preferably parenteral administration, to the patient of an effective amount of high density lipoprotein (HDL).
Claims16
A method for the treatment of endothelial dysfunction in a Type 2 diabetic patient, which comprises administering to a Type 2 diabetic patient suffering from endothelial dysfunction associated with a diabetes-induced macrovascular disorder, an amount of high density lipoprotein (HDL) effective to improve endothelial function, wherein said HDL is administered in a dosage range of from 0.2-100 mg per kg body weight of the patient per treatment, wherein each treatment is separated by at least 7 days.
A method for the treatment of endothelial dysfunction in a Type 2 diabetic patient, which comprises administering to a Type 2 diabetic patient suffering from endothelial dysfunction associated with a diabetes-induced macrovascular disorder, an amount of high density lipoprotein (HDL) effective to improve endothelial function, wherein said HDL is administered in a dosage range of from 10-80 mg per kg body weight of the patient per treatment, wherein each treatment is separated by at least 7 days.
Dependencies are inferred from the claim text.