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US 8,557,838 B2Granted
Immune response modifier formulations containing oleic acid and methods
AssigneeMedicis Pharmaceutical Corporation
InventorsAlexis S. Statham, Robert J. Nelson
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Abstract
Pharmaceutical formulations and methods including an immune response modifier (IRM) compound and an oleic acid component are provided where stability is improved by using oleic acid have low polar impurities such as peroxides.
Claims18
A pharmaceutical formulation comprising:
- a therapeutically effective amount of 1-(2-methylpropyl)-1H imidazo[4,5-c]quinolin-4-amine (imiquimod);
- and
- a pharmaceutically acceptable vehicle including an oleic acid component, wherein the oleic acid component is super refined oleic acid NF.
Dependencies are inferred from the claim text.