Use of allopurinol for the treatment of palmar plantar erythrodysesthesia
AssigneeNobera Pharma, S.L.
InventorYolanda Rodemer
Life of this patent
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Abstract
Use of allopurinol or a pharmaceutically acceptable salt thereof for the treatment or prevention of palmar plantar erythrodysesthesia induced by chemotherapy. The allopurinol or its salt is administered topically to the affected areas, palms and soles, preferably in the form of a cream.
Claims22
A pharmaceutical composition for topical administration to the skin of a subject to treat chemotherapy-induced palmar plantar erythrodysesthesia (PPE) (hand and foot syndrome), comprising 1-10% by weight of the pharmaceutical composition of allopurinol or a pharmaceutically acceptable salt thereof, wherein the pharmaceutical composition is formulated for topical administration to the skin of a subject, and is free of methylsulfonylmethane or cetomacrogol.
A pharmaceutical composition for topical administration to the skin of a subject to treat chemotherapy-induced palmar plantar erythrodysesthesia (PPE) (hand and foot syndrome), comprising 1-10% by weight of the pharmaceutical composition of allopurinol or a pharmaceutically acceptable salt thereof, wherein the pharmaceutical composition is formulated for topical administration to the skin of a subject, and is free of methylsulfonylmethane and cetomacrogol.
Dependencies are inferred from the claim text.