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US 8,557,815 B2Granted
Substituted triazolophthalazine derivatives
AssigneeConcert Pharmaceuticals, Inc.
InventorScott L. Harbeson
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Abstract
This invention relates to novel substituted triazolophthalazines and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering selective α5 receptor partial or full inverse agonists.
Claims5
A compound of Formula Ia,
- or a pharmaceutically acceptable salt thereof, wherein:
- R5 is selected from CD3 and CH3;
- R8 is CD3;
- W is —CY1Y2—, wherein Y1 and Y2 are the same and are selected from hydrogen and deuterium;
- and
- Y3 is hydrogen or deuterium;
- wherein there is at least 50.1% incorporation of deuterium at any atom designated as D or deuterium.
4 more elements
Dependencies are inferred from the claim text.