Immunemodulating oligosaccharides
AssigneeN.V. Nutricia
InventorsBernd Stahl, Laura M'Rabet, Arjan Paul Vos, Johan Garssen, Günther Boehm
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Abstract
The present invention relates to a method for enhancing the immune system and the treatment and/or prevention of immune system related disorders in a mammal, particularly newborns, said method comprising the administration of acid oligosaccharide and neutral oligosaccharide. Food compositions suitable for use in the above method are also provided.
Claims13
A method for the treatment of an immune system-related disorder selected from the group consisting of allergy Type 1, allergy Type 2, allergy Type 3, and allergy Type 4 in a mammal, comprising administering to said mammal a composition comprising a therapeutically effective amount of an acid oligosaccharide and at least two chemically distinct neutral oligosaccharides, wherein:
- the acid oligosaccharide has a degree of polymerization between 1 and 250 and is prepared from pectin or alginate and comprises at least one terminal uronic acid unit selected from the group consisting of galacturonic acid, guluronic acid and mannuronic acid;
- and
- the at least two chemically distinct neutral oligosaccharides comprise fructooligosaccharides and a second oligosaccharide selected from the group consisting of transgalactooligosaccharides, galactooligosaccharides and mixtures thereof.
Dependencies are inferred from the claim text.