Glycyrrhizinates of morphinan derivatives
AssigneeStandard Chem. & Pharm. Co., Ltd.
InventorsChin-Tsai Fan, Cheng-Shun Lai, Wen-Yen Yeh, Yu-Ying Liu
Life of this patent
Estimating the term…
Abstract
The present invention provides a pharmaceutically acceptable compound, a pharmaceutical composition comprising the above-mentioned pharmaceutically acceptable compound. The pharmaceutically acceptable compound provided by the present invention is a salt of a basic group-containing morphinan derivative and a carboxyl group-containing glycyrrhizinic acid and has the ability to be used to manufacture medicaments for treating and/or preventing cough, ameliorating pains, treating respiratory system diseases, treating cardiovascular diseases and treating liver diseases.
Claims11
A pharmaceutically acceptable compound, which is a salt of a basic compound of a derivative of morphinan and a carboxyl group-containing agent of formula (I):
- wherein the derivative of morphinan is selected from the group consisting of dextromethorphan, 3-methoxy-morphinan, dimemorfan, 3-methyl-morphinan, codeine, buprenorphine, butorphanol, nalbuphine, naloxone, nalmefene, naltrexone and oxymorphone.
Dependencies are inferred from the claim text.