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US 8,557,777 B2Granted
Methods for treating cancer using prostate specific antigen and tumor endothelial marker peptides
AssigneeThe Board of Trustees of the University of Illinois
InventorsSupriya M. Perambakam, David J. Peace
Life of this patent
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Abstract
The present invention is directed to prostate specific antigen (PSA) and tumor endothelial marker 8 (TEM8) peptide compositions and methods for treating cancer with the compositions.
Claims18
A composition for treating cancer comprising:
- (i) a pharmaceutically acceptable carrier,
- (ii) prostate specific antigen (PSA) peptide PSA 146-154 (SEQ ID NO:
- 3), and
- (iii) PSA peptide PSA 154-173 (SEQ ID NO:
- 1), PSA peptide PSA 210-230 (SEQ ID NO:
- 2), tumor endothelial marker 8 (TEM8) peptide TEM8 298-306 (SEQ ID NO:
- 18), or combinations thereof.
4 more elements
A kit comprising a composition, instructions for administration of the composition for treating cancer, and a device for administering the composition to a patient, wherein the composition comprises:
- (i) a pharmaceutically acceptable carrier,
- (ii) prostate specific antigen (PSA) peptide PSA 146-154 (SEQ ID NO:
- 3), and
- (iii) PSA peptide PSA 154-173 (SEQ ID NO:
- 1), PSA peptide PSA 210-230 (SEQ ID NO:
- 2), tumor endothelial marker 8 (TEM8) peptide TEM8 298-306 (SEQ ID NO:
- 18), or combinations thereof.
4 more elements
A method of treating prostate cancer comprising administering to a patient in need thereof an effective amount of peptides comprising:
- (i) prostate specific antigen (PSA) peptide PSA 146-154 (SEQ ID NO:
- 3), and
- (ii) PSA peptide PSA 154-173 (SEQ ID NO:
- 1), PSA peptide PSA 210-230 (SEQ ID NO:
- 2), tumor endothelial marker 8 (TEM8) peptide TEM8 298-306 (SEQ ID NO:
- 18), or combinations thereof.
3 more elements
Dependencies are inferred from the claim text.