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AssigneeSeikagaku Corporation
InventorsShigeyuki Wakitani, Masashi Nawata, Kyosuke Miyazaki, Hiroyuki Masuda, Hiroshi Fujita, Yasuhiro Kurahashi
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An object of the present invention is to provide a detection method capable of detecting articular cartilage degeneration or damage in which the abnormality cannot be detected in a radiograph in a simple method and with high accuracy, a method of evaluating the rate of progression of articular cartilage degeneration or damage, and the like. The present invention as a means for achieving the object provides a method of detecting articular cartilage degeneration or damage which cannot be detected in a radiograph, by using the concentration of keratan sulfate in a sample derived from blood as an index, and the like. Further, the present invention provides a method of evaluating the rate of progression of articular cartilage degeneration or damage by using the concentration of keratan sulfate in a sample derived from blood as an index, and the like.
A method of detecting articular cartilage degeneration or damage which cannot be detected in a radiograph, by using a concentration of keratan sulfate in a test sample derived from blood as an index, the method comprising:
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