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US 8,557,302 B2Granted
Andrographis paniculata extract
AssigneeNutrition Science Partners Limited
InventorsJifeng Duan, Zhiming Ma, Xiaoqiang Yan, Weihan Zhang, Tao Wang, Yu Cai
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Abstract
An extract of Andrographis paniculata extract containing andrographolide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographolide, neoandrographolide, polysacchorides, and flavanoids. Also disclosed is a pharmaceutical composition containing such an extract and its use for treating inflammatory bowel disease.
Claims2
A method of treating ulcerative colitis comprising orally administering to a human in recognized need of such treatment an effective amount for treating of a solid dosage form comprising:
- (1) an extract of Andrographis paniculata comprising andrographolide lactones:
- wherein said andrographolide lactones comprise:
- andrographolide in an amount ranging from 6% to 20% of the dry weight of the extract;
- 14-deoxyandrographolide in an amount ranging from greater than 0 to less than 1% of the dry weight of the extract;
- 14-deoxy-11,12-dehydrogen-andrographolide in an amount ranging from 1% to 6% of the dry weight of the extract;
- and
- neoandrographolide in an amount ranging from 1% to 5% of the dry weight of the extract, and
- (2) wherein said solid dosage form for treating ulcerative colitis in a human further comprises at least one pharmaceutically acceptable carrier.
5 more elements
Dependencies are inferred from the claim text.